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Sheng and coauthors compare the copy number intensities of genes associated with GAD67 regulation in the stratum oriens of sectors CA3/2 and CA1 in patients with schizophrenia, patients with bipolar disorder, and healthy controls. Samples of sectors CA3/2 and CA1 were obtained from patients with schizophrenia, patients with bipolar disorder, and healthy controls.
Gibbons et al determine the short-term efficacy of antidepressants for treating major depressive disorder in youth, adult, and geriatric populations. In a companion article, they determine the short-term safety of antidepressants by standard assessments of suicidal thoughts and behavior in these populations and the mediating effect of changes in depressive symptoms.
Nosarti and coauthors investigate the relationships among gestational age, nonoptimal fetal growth, Apgar score, and various psychiatric disorders in young adult life using population-based data from Sweden.
Fagundes and colleagues address associations among recent severe life events, childhood parental emotional maltreatment, depression, and messenger RNA coding for immune markers associated with basal cell carcinoma tumor progression and regression.