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  • Substance Index
  • Background
  • How to contact NTIS
  • Draft Profiles
    • CERCLA Set 24
    • CERCLA Set 25
    • CERCLA Set 26
    • CERCLA Set 27
    • DoD5
  • Federal Register Notices
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Toxicological Profiles

 

Information About Contaminants Found at Hazardous Waste Sites


Substance Index for ToxProfiles

Finalized toxicological profiles by chemical with NTIS order number. Updates are in bold.
* denotes tox profiles funded by the Department of Defense.


  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. L
  12. M
  13. N
  14. O
  15. P
  16. R
  17. S
  18. T
  19. U
  20. V
  21. W
  22. X
  23. Z

 

A

  • Acetone (PB/95/100095/AS)

  • Acrolein (Updated) (PB2008-100001)

  • Acrylamide (PB2013-107047)

  • Acrylonitrile (PB/91/180489/AS)

  • Aldrin/Dieldrin (Updated) (PB2003-100134)

  • Aluminum (Updated) (PB2009-100001)

  • Americium (PB2004-104396)

  • Ammonia (Updated) (PBPB2004-107331)

  • Antimony (PB/93/110641/AS)

  • Arsenic (Updated) (PB2008-100002)

  • Asbestos (Updated) (PB/2001/109101)

  • Atrazine (PB2004-100001)


 

B

  • 1,3-Butadiene (Updated) (PB2013-105789)

  • 2,3-Benzofuran (PB/93/110666/AS)

  • 2-Butanone (PB/93/110708/AS)

  • 2-Butoxyethanol (PB/99/102527/AS)*

  • Barium (Updated) (PB2008-100003)

  • Benzene (Updated) (PB2008-100004)

  • Benzidine (Updated) (PB/2001/109102)

  • Beryllium (Updated) (PB2003-100135)

  • Bis(2-chloroethyl) Ether (PB/90/168683/AS)

  • Bis(chloromethyl) Ether (PB/90/168691/AS)

  • Boron (Updated) (PB2010-100001)

  • Bromodichloromethane (PB/90/167461/AS)

  • Bromoform & Dibromochloromethane (Updated) (PB2006-100001)

  • Bromomethane (PB/93/110682/AS)


 

C

  • Cadmium (Updated) (PB2013-105787)

  • Carbon Disulfide (PB97-121073)

  • Carbon Monoxide (PB2013-105795)

  • Carbon Tetrachloride (Updated) (PB2006-100002)

  • Cesium (PB2004-104397)

  • Chlordane (Updated) (PB/95/100111/AS)

  • Chlordecone (PB/95/264354)

  • Chlorfenvinphos (PB/98/101116/AS)

  • Chlorinated Dibenzo-p-dioxins (CDDs) (Updated) (PB/99/121998)

  • Chlorine (PB2010-100002)

  • Chlorine Dioxide & Chlorite (PB 2004-107332)

  • Chlorobenzene (PB/91/180505/AS)

  • Chlorodibenzofurans (CDFs) (PB/95/100129/AS)

  • Chloroethane (Updated) (PB/99/121956)

  • Chloroform (Updated) (PB/98/101140/AS)

  • Chloromethane (Updated) (PB/99/121964)

  • Chlorophenols (Updated) (PB/99/166639)

  • Chlorpyrifos (PB/98/103088/AS)

  • Chromium (PB2013-105788)

  • Cobalt (Updated) (PB 2004-10733)

  • Copper (Updated) (PB 2004-10733)

  • Creosote (Updated) (PB2003-100136)

  • Cresols (Updated) (PB2009-100002)

  • Cyanide (Updated) (PB2007-100674)


 

D

  • 1,1-Dichloroethane (Draft for Public Comment)

  • 1,1-Dichloroethene (Updated) (PB/95/100152/AS)

  • 1,2-Dibromo-3-Chloropropane (PB/93/110906/AS)

  • 1,2-Dibromoethane (PB/93/110740/AS)

  • 1,2-Dichloroethane (Updated) (PB/2001/109103/AS)

  • 1,2-Dichloroethene (Updated) (PB/97/121081/AS)

  • 1,2-Dichloropropane (PB/90/182122/AS)

  • 1,2-Diphenylhydrazine (Updated) (PB/91/180356/AS)

  • 1,3 Dinitrobenzene & 1,3,5 Trinitrobenzene (PB/95/264289/AS)*

  • 1,4-Dioxane (PB2013-105794)

  • 3,3'-Dichlorobenzidine (Updated) (PB/99/121980)

  • DDT, DDE, DDD (Updated) (PB2003-100137)

  • Di(2-ethylhexyl)phthalate (DEHP) (Updated) (PB2003-100138)

  • Di-n-butyl Phthalate (Updated) (PB/2001/109104/AS)

  • Di-n-octylphthalate (DNOP) (PB/98/101033/AS)*

  • Diazinon (Updated) (PB2009-100003)

  • Dichlorobenzenes (Updated) (PB2007-100672)

  • Dichloropropenes (Updated) (PB2009-100004)

  • Dichlorvos (PB/98/101124/AS)

  • Diethyl phthalate (PB/95/264214/AS)*

  • Diisopropyl Methylphosphonate (DIMP) (PB/99/102535/AS)*

  • Dinitrocresols (Updated) (PB/95/264321)

  • Dinitrophenols (PB/95/264339)

  • Dinitrotoluenes (Updated) (Draft for Public Comment)*

  • Disulfoton (PB/95/264347)


 

E

  • Endosulfan (Updated) (Draft for Public Comment)

  • EndrinEndrin aldehyde (Updated) (PB/97/121040/AS)

  • Ethion (PB/2000/108024)

  • Ethylbenzene (PB2010-100004)

  • Ethylene Glycol (PB2010-100005)

  • Ethylene Oxide (PB/91/180554/AS)


 

F

  • Fluorides, Hydrogen Fluoride, and Fluorine (Updated) (PB2004-100002)

  • Formaldehyde (PB/99/166654)

  • Fuel Oils / Kerosene (PB/95/264222/AS)*


 

G

  • Gasoline, Automotive (PB/95/264206/AS)*

  • Guthion (PB2009-100005)


 

H

  • 2-Hexanone (Updated) (PB/93/110773/AS)

  • Heptachlor/Heptachlor Epoxide (Updated) (PB2008-100005)

  • Hexachlorobenzene (Updated) (Draft for Public Comment)

  • Hexachlorobutadiene (PB/95/100160/AS)

  • Hexachlorocyclohexane (HCH) (Updated) (PB2006-100003)

  • Hexachlorocyclopentadiene (HCCPD) (PB/99/166670)

  • Hexachloroethane (PB/98/101041/AS)*

  • Hexamethylene Diisocyanate (HDI) (PB/99/102543/AS)*

  • HMX (Octogen) (PB/98/101058/AS)*

  • Hydraulic Fluids (PB/98/101066/AS)*

  • Hydrazines (PB/98/101025/AS)*

  • Hydrogen Sulfide (Updated) (PB2007-100675)

  • n-Hexane (PB/99/166688)


 

I

  • Iodine (PB2004-104399)

  • Ionizing Radiation (PB/99/163388)

  • Isophorone (PB/90/180225/AS)


 

J

  • Jet Fuels JP-4 and JP-7 (PB/95/264230/AS)*

  • Jet Fuels JP-5 and JP-8 (PB/95/264230/AS)*


 

L

  • Lead (Updated) (PB2008-100007)


 

M

  • 4,4'-Methylenebis(2-Chloroaniline)(MBOCA) (PB/95/100186/AS)

  • 4,4'-Methylenedianiline (PB/99/102568/AS)*

  • Malathion (PB2004-100003)

  • Manganese (Updated) (PB2013-105793)

  • Mercury (Updated) (PB/99/142416)

  • Methoxychlor (Updated) (PB2003-100140)

  • Methyl Mercaptan (PB/93/110799/AS)

  • Methyl Parathion (PB/2001/109105/AS)

  • Methyl tert-Butyl Ether (MTBE) (PB/97/121016/AS)

  • Methylene Chloride (Updated) (PB/2000/108026)

  • Mirex (PB/95/264354)


 

N

  • n-Nitrosodi-n-propylamine (PB/90/180258/AS)

  • n-Nitrosodimethylamine (PB/90/182130/AS)

  • n-Nitrosodiphenylamine (Updated) (PB/93/182509/AS)

  • Naphthalene, 1-Methylnapthalene, 2-Methylnapthalene (Updated) (PB2006-100004)

  • Nickel (Updated) (PB2006-100005)

  • Nitrobenzene (PB/91/180398/AS)

  • Nitrophenols (PB/93/110823/AS)


 

O

  • Otto Fuel II and its Components (PB/95/264248/AS)*


 

P

  • Pentachlorophenol (Updated) (PB/2001/109106/AS)

  • Perchlorates (Updated) (PB2009-100006)

  • Perfluoroalkyls (Draft for Public Comments)

  • Phenol (Updated) (PB2009-100007)

  • Phosphate Ester Flame Retardants (PB2013-105796)

  • Plutonium (Updated) (PB2010-100006)

  • Polybrominated Biphenyls (PBBs) & Polybrominated Diphenyl Ethers (PBDEs) (Updated) (PB2004-107334)

  • Polychlorinated Biphenyls (PCBs) (Updated) (PB/2000/108027)

  • Polycyclic Aromatic Hydrocarbons (PAHs) (Updated) (PB/95/264370)
    Acenaphthene, Acenaphthylene, Anthracene, Benzo(a)anthracene, Benzo(a)pyrene, Benzo(b)fluoranthene, Benzo(g,h,i)perylene, Benzo(k)fluoranthene, Chrysene, Dibenzo(a,h)anthracene, Fluoranthene, Fluorene, Indeno(1,2,3-cd)pyrene, Phenanthrene, Pyrene

  • Propylene Glycol (Updated) (PB2009-103929)*

  • Pyrethrins and Pyrethroids (PB2004-100004)

  • Pyridine (PB/93/110831/AS)


 

R

  • Radium (PB/91/180414/AS)

  • Radon (PB2013-104879)

  • RDX (Cyclonite) (PB2012-105630)*


 

S

  • Selenium (Updated) (PB2004-100005)

  • Silver (PB/91/180430/AS)

  • Stoddard Solvent (PB/95/264263)*

  • Strontium (PB2004-104400)

  • Styrene (PB2010-100007)

  • Sulfur Dioxide (PB/99/122020)

  • Sulfur Mustard (Updated) (PB2004-100006)

  • Sulfur Trioxide & Sulfuric Acid (PB99/122038)

  • Synthetic Vitreous Fibers (PB2004-107335)


 

T

  • 1,1,1-Trichloroethane (Updated) (PB/95/264396)

  • 1,1,2,2-Tetrachloroethane (Updated) (PB2009-100008)

  • 1,1,2-Trichloroethane (PB/90/196411/AS)

  • 1,2,3 Trichloropropane (PB/93/110872/AS)

  • 1,3,5 Trinitrobenzene & 1,3 Dinitrobenzene (PB/95/264289/AS)*
    (See 1,3-Dinitrobenzene)

  • 2,4,6-Trinitrotoluene (TNT) (PB/95/264297/AS)*

  • Tetrachloroethylene (PERC) (Updated) (PB/98/101181/AS)

  • Tetryl (PB/95/264271/AS)*

  • Thallium (PB/93/110856/AS)

  • Thorium (PB/91/180448/AS)

  • Tin and Compounds (Updated) (PB2006-100006)

  • Titanium Tetrachloride (PB/98/101082/AS)*

  • Toluene (Updated) (PB/2000/108028)

  • Total Petroleum Hydrocarbons (TPH) (PB/99/163370)

  • Toxaphene (Updated) (Draft for Public Comments)

  • Trichlorobenzenes (Draft for Public Comments)

  • Trichloroethylene (TCE) (Updated) (PB/98/101165/AS)

  • Tungsten (PB2006-100007)


 

U

  • Uranium (Updated) (PB2013-105792)

  • Used Mineral-based Crankcase Oil (PB/98/101074/AS)*


 

V

  • Vanadium (PB2013-105790)

  • Vinyl Acetate (PB/93/110898/AS)

  • Vinyl Chloride (Updated) (PB2007-100671)


 

W

  • White Phosphorus (PB/98/101090/AS)*


 

X

  • Xylenes (Updated) (PB2008-100008)


 

Z

  • Zinc (Updated) (PB2006-100008)

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Background

By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.

So far, 326 toxicological profiles have been published or are under development as finals or drafts for public comment; 300 profiles were published as finals; 140 profiles have been updated. Currently, 7 profiles are being revised based on public comments received; 12 profiles under development These profiles cover more than 300 substances.

Toxicological profiles are developed in two stages:

(1) DRAFTS: The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90 day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology and Human Health Sciences.

(2) FINALS: After the 90 day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles. Profiles are available online at: www.atsdr.cdc.gov/toxprofiles/index.asp or on CD-ROM

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NTIS address

NTIS distributes finalized toxicological profiles for a fee. For more information, contact

National Technical Information Service
5285 Port Royal Road
Springfield, Virginia 22161
1-800-553 6847 or 703-605-6000
Web site: www.ntis.gov

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Toxicological profiles "Draft for Public Comment" - CERCLA Set 24

  • Trichlorobenzenes
  • Toxaphene (Update)
  • Perfluoroalkyls

The public comment period has ended and the profiles will be revised based on relevant public comments.


Toxicological profiles (under development) CERCLA Set 25

  • 1,1-Dichloroethane
  • Dinitrotoluenes
  • Endosulfan
  • Hexachlorobenzene

The public comment period has ended and the profiles will be revised based on relevant public comments.


Toxicological profiles (under development) CERCLA Set 26

  • Glutaraldehyde
  • Hydrogen Sulfide/Carbonyl Sulfide (Update)
  • Parathion
  • Tetrachloroethylene (Update)
  • Trichloroethylene (Update)

Toxicological profiles (under development) CERCLA Set 27

  • DEET
  • Toluene Diisocyanate
  • Nitrates/Nitrites
  • Toluene (Update)
  • Polybrominated Diphenyl Ethers (Update)
  • Molybdenum

Department of Defense (under development) – DoD5

  • Jet Fuels (JP5/8) (Update)

List updated on June 20, 2014

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Federal Register Notices:

  • FRN RDX [PDF, 51 KB]
  • FRN Uranium [PDF, 52 KB]
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