Table of Contents

IN THIS ISSUE

• pancRNAs in early development

  Development 2015 142:e0501
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• Uncovering neurogenic potential of striatal astrocytes

  Development 2015 142:e0502
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• Timing degradation to tune development

  Development 2015 142:e0503
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• Getting to the heart of heart cell identity

  Development 2015 142:e0504
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• Asymmetric division and fate in the retina

  Development 2015 142:e0505
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MEETING REVIEW

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  • Catherina G. Becker and
  • Ruth Diez del Corral

  Neural development and regeneration: it's all in your spinal cord

  Development 2015 142:811-816; doi:10.1242/dev.121053
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  Summary: A recent EMBO Workshop highlighted the latest advances in our understanding of spinal cord development and regeneration, and the techniques used to study it.

REVIEW

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  • Elena Kozhemyakina,
  • Andrew B. Lassar,
  • and Elazar Zelzer

  A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

  Development 2015 142:817-831; doi:10.1242/dev.105536
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  Summary: This Review article discusses how signaling molecules, mechanical signals and morphological cell features are integrated to regulate chondrogenesis and bone development.

STEM CELLS AND REGENERATION

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  • Alessio Paolini,
  • Anne-Laure Duchemin,
  • Shahad Albadri,
  • Eva Patzel,
  • Dorothee Bornhorst,
  • Paula González Avalos,
  • Steffen Lemke,
  • Anja Machate,
  • Michael Brand,
  • Saadettin Sel,
  • Vincenzo Di Donato,
  • Filippo Del Bene,
  • Flavio R. Zolessi,
  • Mirana Ramialison,
  • and Lucia Poggi

  Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function

  Development 2015 142:832-839; posted ahead of print February 5, 2015, doi:10.1242/dev.118612
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  • Supplementary Material

  Highlighted article: The cytokinesis protein Anillin regulates asymmetric cell division in the zebrafish retina, promoting progenitor renewal and influencing retinal ganglion cell differentiation.

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  • Giulia Nato,
  • Alessia Caramello,
  • Sara Trova,
  • Valeria Avataneo,
  • Chiara Rolando,
  • Verdon Taylor,
  • Annalisa Buffo,
  • Paolo Peretto,
  • and Federico Luzzati

  Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington's disease

  Development 2015 142:840-845; posted ahead of print February 5, 2015, doi:10.1242/dev.116657
  • Abstract
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  • Supplementary Material

  Highlighted article: Brain lesion in mice reveals a latent neurogenic potential in striatal astrocytes, which can proliferate and generate new neuroblasts.

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  • Guang Li,
  • Karolina Plonowska,
  • Rajarajan Kuppusamy,
  • Anthony Sturzu,
  • and Sean M. Wu

  Identification of cardiovascular lineage descendants at single-cell resolution

  Development 2015 142:846-857; posted ahead of print January 29, 2015, doi:10.1242/dev.116897
  • Abstract
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  • Supplementary Material

  Highlighted article: Multiplex gene expression analysis on single cardiac lineage cells provides a high-resolution view of cardiac fate choice in the mouse embryo and during stem cell differentiation.

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  • Laurence A. Lemaire,
  • Joan Goulley,
  • Yung Hae Kim,
  • Solenne Carat,
  • Patrick Jacquemin,
  • Jacques Rougemont,
  • Daniel B. Constam,
  • and Anne Grapin-Botton

  Bicaudal C1 promotes pancreatic NEUROG3⁺ endocrine progenitor differentiation and ductal morphogenesis

  Development 2015 142:858-870; doi:10.1242/dev.114611
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  • Supplementary Material

  Summary: Inactivation of the Bicc1 gene, which is associated with kidney displasia in humans, causes pancreatic endocrine differentiation defects leading to cyst formation.

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  • Matias G. De Vas,
  • Janel L. Kopp,
  • Claire Heliot,
  • Maike Sander,
  • Silvia Cereghini,
  • and Cécile Haumaitre

  Hnf1b controls pancreas morphogenesis and the generation of Ngn3⁺ endocrine progenitors

  Development 2015 142:871-882; doi:10.1242/dev.110759
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  • Supplementary Material

  Summary: Mice with conditional depletion of the transcription factor Hnf1b, whose mutation is associated with maturity-onset diabetes of the young in humans, show multiple defects in pancreas development.

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  • Tamar Lengil,
  • Dana Gancz,
  • and Lilach Gilboa

  Activin signaling balances proliferation and differentiation of ovarian niche precursors and enables adjustment of niche numbers

  Development 2015 142:883-892; posted ahead of print January 29, 2015, doi:10.1242/dev.113902
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  • Supplementary Material

  Summary: In the Drosophila ovary, terminal filament cell development is regulated by activin, which, along with the hormone ecdysone, controls expression of the key transcription factor Broad-Z1.

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  • Linsey E. Lindley,
  • Kevin M. Curtis,
  • Avencia Sanchez-Mejias,
  • Megan E. Rieger,