| # |
GPM |
# proteins |
Description |
|
1. |
GPM32010007612
metadata 
peptide
model
group
aaa
gel
mh
go
|
213 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 121_Orbi_0152_wt1_SCX1_01.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
2. |
GPM32010007613
metadata
peptide
model
group
aaa
gel
mh
go
|
123 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 122_Orbi_0152_wt1_SCX1_02.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
3. |
GPM32010007614
metadata
peptide
model
group
aaa
gel
mh
go
|
76 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 123_Orbi_0152_wt1_SCX1_03.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
4. |
GPM32010007615
metadata
peptide
model
group
aaa
gel
mh
go
|
385 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 124_Orbi_0152_wt1_SCX1_04.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
5. |
GPM32010007616
metadata
peptide
model
group
aaa
gel
mh
go
|
730 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 125_Orbi_0152_wt1_SCX1_05.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
6. |
GPM32010007617
metadata
peptide
model
group
aaa
gel
mh
go
|
550 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 126_Orbi_0152_wt1_SCX1_06.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
7. |
GPM32010007618
metadata
peptide
model
group
aaa
gel
mh
go
|
313 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 127_Orbi_0152_wt1_SCX1_07.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
8. |
GPM32010007619
metadata
peptide
model
group
aaa
gel
mh
go
|
342 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 128_Orbi_0152_wt1_SCX1_08.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
9. |
GPM32010007620
metadata
peptide
model
group
aaa
gel
mh
go
|
1108 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 129_Orbi_0152_wt1_SCX1_09.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
10. |
GPM32010007621
metadata
peptide
model
group
aaa
gel
mh
go
|
486 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 130_Orbi_0152_wt1_SCX1_10.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
11. |
GPM32010007622
metadata
peptide
model
group
aaa
gel
mh
go
|
394 |
- BRENDA cell culture: none
- BRENDA tissue: none
- CELL cell type: none
- GO subcellular: none
- email: foppermann@gmx.net
- institution: MPI Biochemistry
- name: Oppermann FS, et al.
- project: Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.
- project comment: Massive Experiment: wt1_SCX1, data file: 131_Orbi_0152_wt1_SCX1_11.RAW. Data published as part of Mol Cell Proteomics 2012 11:O111.012351(PubMed ). From the Abstract: We report a chemical genetics and quantitative phosphoproteomics approach that encompasses cellular kinase activation in combination with comparative replicate mass spectrometry analyses of cells expressing either inhibitor-sensitive or resistant kinase variant. We applied this workflow to Plk1 (Polo-like kinase 1) in mitotic cells and induced cellular Plk1 activity by wash-out of the bulky kinase inhibitor 3-MB-PP1, which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
|
|
12. |
GPM32010007623
metadata
peptide
model
group
aaa
gel
mh
go
|
90 |
|
|
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is neither affiliated with the authors of this page nor responsible
for its contents. This is a safe-cache copy of the original web site.