Plenary & Parallel Session Listing

Wednesday, June 20   7:00 PM–8:00 PM
Overture Hall

Plenary Session I
Imaging and Emerging Technologies

Chair: Bruce Appel

1- 7:00
Why we dip our shrimp in butter: Using zebrafish larvae to uncover an unexpected linkage between dietary fat and cholesterol absorption. James W. Walters, Jennifer L. Anderson, Steven A. Farber.

2- 7:15
In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma. Myron S. Ignatius, Eleanor Chen, Natalie M. Elpek, Adam Fuller, Inês M. Tenente, Ryan Clagg, Sali Liu, Jessica S. Blackburn, Corinne M. Linardic, Andrew Rosenberg, Petur G. Nielsen, Thorsten R. Mempel, David M. Langenau.

3- 7:30
More than the sum of the parts? Real-time imaging of isolated segmentation clock cells in vitro reveals interactions underlying the determination front. Alexis B. Webb, Daniele Soroldoni, Andrew C. Oates.

4- 7:45
Zebrabow: multispectral cell labeling for lineage analysis and neural circuit tracing in zebrafish. Albert Pan, Tom Freundlich, Tamily Weissman, David Schoppik, Cindy Wang, Brian Ciruna, Dawen Cai, Jeff Lichtman, Joshua Sanes, Alexander Schier.

Wednesday, June 20   8:00 PM–9:00 PM
Overture Hall

Keynote Speaker: Cori Bargmann

Introduction: Alex Schier

Thursday, June 21   8:30 AM–9:45 AM
Overture Hall

Neural Circuits, Neurophysiology and Behavior

Chair: Stephan Neuhauss

5- 8:30
Telencephalic projection neurons become tuned at the onset of the conditioned stimulus by the active avoidance learning. T. Aoki, M. Kinoshita, R. Aoki, M. Agetsuma, H. Aizawa, M. Yamazaki, A. Arata, S. Higashijima, H. Okamoto.

6- 8:45
Habenular asymmetry and neuropilin signaling affect target selection and activity of olfactory neurons. Tagide deCarvalho, Christine Thisse, Bernard Thisse, Marnie Halpern.

7- 9:00
Dark photokinesis behavior in larval zebrafish does not require the eyes or the pineal. K. Fero, A. Fernandes, A. Arrenberg, S. Bergeron, E. Beddows, W. Driever, H. Burgess.

8- 9:15
The Conserved Dopaminergic Diencephalospinal Tract Mediates Vertebrate Locomotor Development In Zebrafish Larvae. Aaron M. Lambert, Joshua L. Bonkowsky, Mark A. Masino.

9- 9:30
Genetic factors of tobacco dependence and treatment response in zebrafish. Margot A. Cousin, Amanda R. Wiinamaki, Mark D. Urban, David P. Argue, Kimberly J. Skuster, Karl J. Clark, Jon O. Ebbert, Stephen C. Ekker, Eric W. Klee.

Thursday, June 21   8:30 AM–9:45 AM
Capitol Theater

Cardiac Development, Function and Disease

Chair: Deborah Yelon

10- 8:30
An Expression-based Mutagenesis Screen to Identify Cardiac Mutants with Either Developmental or Adult Phenotypes in Zebrafish. Yonghe Ding, Weibin Liu, Yun Ding, Beninio Jomoke, Jingchun Yang, Wei Huang, Karl Clark, Xueying Lin, Stephen Ekker, Xiaolei Xu.

11- 8:45
Identifying novel cardiovascular gene functions through systematic phenotype prediction. G. Musso, M. Tasan, J. Beaver, FP Roth, CA MacRae.

12- 9:00
tal1 regulates the formation of intercellular junctions and the maintenance of identity in the endocardium. Joshua Bloomekatz, Jennifer Schumacher, Zayra Garavito-Aguilar, Deborah Yelon.

13- 9:15
The S1P1 receptor is required for sarcomere assembly in developing cardiomyocytes. Hilary Clay, Didier Stainier, Coughlin Shaun.

14- 9:30
Activation of voltage-dependent anion channel 2 suppresses Ca²⁺-induced cardiac arrhythmia. J. Schredelseker, H. Shimizu, J. Huang, K. Lu, S. Franklin, T. Vondriska, J. Goldhaber, O. Kwon, J. Chen.

Thursday, June 21   8:30 AM–9:45 AM
Playhouse Theater

Cilia, Cell and Tissue Polarity

Chair: Rebecca Burdine

15- 8:30
CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. J. Panizzi, A. Becker-Heck, Y. Liu, N. Pathak, C. Austin-Tse, F. Olale, R. Burdine, A. Schier, C. O'Callaghan, H. Mitchison, S. King, H. Omran, I. Drummond.

16- 8:45
The TOR signaling pathway modulates cilia length and function. Shiaulou Yuan, Jade Li, Dennis Diener, Michael Choma, Joel Rosenbaum, Zhaoxia Sun.

17- 9:00
Non-Telomeric TRF1 in Cilia Is Essential for Early Vertebrate Development. Jie Qi, Lishu Li, Delgado Valdez, Guang-Qing Xia, Tadatuki Tsujita, Michael Rebagliati, Shuji Kishi.

18- 9:15
Microtubule-mediated trafficking of Rab11a endosomes is critical for zebrafish hindbrain lumen opening. Clare E. Buckley, Xiaoyun Ren, Brian S. Clark, Brian A. Link, Jonathan D. Clarke.

19- 9:30
Live imaging of Rab8 trafficking defects in cc2d2a mutant zebrafish. Ruxandra Bachmann-Gagescu, Ian Phelps, Austin Forbes, Dan Doherty, Cecilia Moens.

Thursday, June 21   10:30 AM–11:45 AM
Overture Hall

Plenary Session II
Signaling and Gene Regulation

Chair: Peter Currie

20- 10:30
A novel role for the chromosomal passenger protein Birc5b in reorganizing microfilaments and germ plasm in the zebrafish embryo. Sreelaja Nair, Florence Marlow, Elliott Abrams, Lee Kapp, Mary Mullins, Francisco Pelegri.

21- 10:45
The small molecule primordazine ablates primordial germ cells through a novel regulatory element in the nanos1 3’ UTR. Y. Jin, P. Schlueter, N. Jurisch-Yaksi, S.-E. Ong, S. Carr, R. Peterson.

22- 11:00
Gpr125 modulates the planar cell polarity signaling potentially by promoting supramolecular complex formation. Xin Li, Diane Sepich, Mingwei Ni, Heidi Hamm, Florence Marlow, Lilianna Solnica-Krezel.

23- 11:15
Live imaging of endogenous active Rho in neural crest cells in vivo reveals Rho functions during EMT. Matthew R. Clay, Mary C. Halloran.

24- 11:30
LH3 dependent ECM modifications are critical for peripheral motor nerve regeneration. Jesse Isaacman-Beck, Michael Granato.

Thursday, June 21   1:30 PM–2:45 PM
Overture Hall

Regeneration and Stem Cells

Chair: Ken Poss

25- 1:30
Translational profiling of cardiomyocytes identifies a Jak-Stat paracrine feedback relay controlling zebrafish heart regeneration. Yi Fang, Vikas Gupta, Ravi Karra, Taylor Wahlig, Jennifer Holdway, Kenneth Poss.

26- 1:45
The role of Hyaluronic Acid in cardiac regeneration. Maria A. Missinato, Julie Marco, Nicla Romano, James A. Carroll, Michael Tsang.

27- 2:00
Adult hypothalamic neural stem cell generates GnRH-Neurons. Christian Cortés-Campos, Kathleen Whitlock.

28- 2:15
Identification of quantitative genetic variations regulating hematopoietic regeneration. Teresa V. Bowman, Jennifer N. Cech, Corey S. Martin, Anna K. Sessa, Jocelyn L. Leblanc, Yi Zhou, Leonard I. Zon.

29- 2:30
Twist genes facilitate skeletal muscle regeneration via myocyte dedifferentiation - a link between tissue repair and cancer. Daniel Kasprick, Steven Grzegorski, Phillip Kish, Tyler Junttila, Lindsay Ward, Brenda Bohnsack, Alon Kahana.

Thursday, June 21   1:30 PM–2:45 PM
Capitol Theater

Neural Development

Chairs: Masahiko Hibi and Vincent Cunliffe

30- 1:30
Robustness in retinoic acid-dependent hindbrain patterning. Kelly Radtke, Lei Zhang, Anna Cai, Qing Nie, Tom Schilling.

31- 1:45
Regulation of neural progenitor survival by zebrafish cerebrospinal fluid. Jessica Chang, Hazel Sive.

32- 2:00
Intra-lineage Directional Notch Signaling Regulates Self-renewal and Differentiation of Asymmetrically Dividing Radial Glia. Z. Dong, N. Yang, S. Yeo, A. Chitnis, S. Guo.

33- 2:15
miR-9 balances proliferation, differentiation and quiescence in neural progenitors. Marion Coolen, Shauna Katz, Denis Thieffry, Øyvind Drivenes, Thomas Becker, Laure Bally-Cuif.

34- 2:30
Genetic mutation of β-SNAP causes photoreceptor degeneration through the activation of the BH3-only SNARE, BNip1. Y. Nishiwaki, A. Yoshizawa, Y. Kojima, E. Oguri, S. Nakamura, S. Suzuki, J. Yuasa-Kawada, M. Kinoshita-Kawada, T. Mochizuki, I. Masai.

Thursday, June 21   1:30 PM–2:45 PM
Playhouse Theater

Signaling in Development and Disease

Chair: Karuna Sampath

35- 1:30
Insights into wnt8a transcriptional and post-transcriptional regulation reveal a novel function for maternal wnt8a. Arne C. Lekven, Anand Narayanan, Anikka D. Butler, Jo-Ann Fleming, Daniel S. Wagner, Patricia Nano, Amy Whitener.

36- 1:45
Naked1 EF-hand function is dispensable for β-catenin activity but is necessary for Wnt/PCP. S. Derry, T. Westfall, D. Slusarski.

37- 2:00
Araf kinase antagonizes Nodal/Smad2 activity in mesendoderm induction and patterning by directly phosphorylating Smad2 linker. Xingfeng Liu, Cong Xiong, Shunji Jia, Yu Zhang, Qiang Wang, Anming Meng.

38- 2:15
simplet is required for regeneration and Wnt signal transduction by regulating β-catenin nuclear localization. Christopher L. Antos, Caghan Kizil, Beate Kuechler, Guenes Oezhan-Kizil, Jia-Jiun Yan, Andrew C. Oates, Enrico Moro, Francesco Argenton, Michael Brand, Gilbert Weidinger.

39- 2:30
Dwarfism and hyperlipogenesis in zebrafish growth hormone 1 mutant vizzini. Sarah K. McMenamin, James Minchin, Tiffany Gordon, John F. Rawls, David M. Parichy.

Thursday, June 21   1:30 PM–2:45 PM
Promenade Hall

Vascular Biology

Chair: Nathan Lawson

40- 1:30
Development of the Common Cardinal Vein in Zebrafish Represents a New Mode of Vessel Formation. C. Helker, T. Kärpänen, D. Zeuschner, S. Schulte-Merker, W. Herzog.

41- 1:45
nft/reck regulates the ECM to enable brain vascularization. Florian Ulrich, Andrew Prendergast, David Raible, Jesús Torres-Vázquez.

42- 2:00
Reverse genetic screen in zebrafish identify role of miR-142 in vascular development and integrity. Mukesh Lalwani, Meenakshi Sharma, Ramcharan Singh, Rajendra Chauhan, Ashok Patowary, Naresh Singh, Vinod Scaria, Sridhar Sivasubbu.

43- 2:15
In vivo imaging in zebrafish reveals plexin D1 regulates adipocyte hypertrophy through MMP-mediated remodelling of the extracellular matrix. James EN Minchin, Christopher J. Harvey, Jesus Torres-Vazquez, John F. Rawls.

44- 2:30
Transdifferentiation of fast skeletal muscle into endothelial cells by ectopic expression of etsrp/etv2. Matthew B. Veldman, Cheng jian Zhao, Shuo Lin.

Friday, June 22   8:30 AM–10:00 AM
Overture Hall

Plenary Session III
Genetics and Genomics

Chair: David Raible

45- 8:30
Exploring the mechanisms and developmental dynamics of coding and non-coding transcription regulation with zebrafish and spotted green pufferfish. Y. Hadzhiev, C. Previti, C. Nepal, N. Li, V. Haberle, H. Takahashi, A. M. Suzuki, S. Anand, J. Gehrig, A. Akalin, J. C. Bryne, O. Armant, S. Rastegar, W. van IJcken, C. Watson, U. Strähle, E. Stupka, P. Carninci, B. Lenhard, F. Müller.

46- 8:45
Genomic resources annotating the zebrafish cis-regulatory landscape. Michael Hiller, Saatvik Agarwal, Jim Notwell, Aaron Wenger, Gill Bejerano.

47- 9:00
The Zebrafish Mutation Project: Systematic genome -wide functional annotation of zebrafish protein-coding genes. Ross Kettleborough, Steven Harvey, Freek van Eeden, Ian Sealy, Ewart de Bruijn, Colin Herd, Fruzsina Fenyes, Richard White, Selina Mehroke, Catherine Scahill, Christopher Dooley, Richard Gibbons, John Collins, Neha Wali, Edwin Cuppen, Elisabeth BuschNentwich, Derek Stemple.

48- 9:15
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Gaurav K. Varshney, Jing Lu, Wuhong Pei, Haigen Hunag, Sunny Hunag, Zhongan Yang, Derek Gildea, David Schoenfeld, Nam Pho, David Casero Diaz-Cano, Tyra Wolfsberg, Deborah Moshbrook-Davis, Li-En Jao, Bo Zhang, Matteo Pellegrini, Shuo Lin, Shawn M. Burgess.

49- 9:30
Conditional gene silencing in zebrafish using spatially and temporally targetable RNA interference. Su Guo, Zhiqiang Dong, Jisong Peng.

Friday, June 22   10:45 AM–12:00 NOON
Overture Hall

Emerging Technologies: Imaging

Chair: Jan Huisken

50- 10:45
An Imaging Framework and Anatomical Atlas for 3D High Resolution Spatial Comparison of Gene Expression in the Larval Zebrafish Brain. W. Driever, K. Liu, M. Rath, D. Ruess, T. Mueller, H. Skribbe, T. Schmidt, A. Filippi, R. Nitschke, T. Brox, H. Burkhardt, O. Ronneberger.

51- 11:00
Ultra long-term imaging in a light sheet microscope. Michaela Mickoleit, Anna Kaufmann, Michael Weber, Jan Huisken.

52- 11:15
Movement of pharyngeal teeth during feeding in zebrafish and medaka revealed by high-speed X-ray microscopy at synchrotron SPring-8. Kohei Hatta, Tatsunori Harada, Takanori Ikenaga, Kentaro Uesugi, Kyohei Fujita, Tamami Yamamoto.

53- 11:30
Visualizing intestinal Caveolin-1 localization and caveolar endocytosis: Using the zebrafish to address cell biological problems in vivo. Jessica P. Otis, Steven A. Farber.

54- 11:45
Real-time visualization of the neuronal activity in the brain during visual perception of a natural object. Akira Muto, Masamichi Ohkura, Gembu Abe, Junichi Nakai, Koichi Kawakami.

Friday, June 22   10:45 AM–12:00 NOON
Capitol Theater

Neural Degeneration, Regeneration and Disease

Chair: Laure Bally-Cuif

55- 10:45
Repression of TGFβ signaling during photoreceptor regeneration. Jenny R. Lenkowski, Christopher J. Sifuentes, Cecilia B. Moens, Pamela A. Raymond.

56- 11:00
Reciprocal Modulations of Wnt Signaling Improve Cell-specific Regeneration Kinetics in the Zebrafish Retina. Jeff Mumm, Junko Ariga.

57- 11:15
Function of Plastin3 in modification of SMA in a zebrafish smn morphant model. Alison N. Lyon, Leslie A. Adams, Ricardo H. Pineda, Christine E. Beattie.

58- 11:30
Reduced excitability of Motor Neurons and Schwann cells in a zebrafish model of Spinal Muscular Atrophy. Kelvin See, Christoph Winkler.

59- 11:45
Hh Signaling Regulates Neurogenesis in the Post-Embryonic Hypothalamus. A. Tuba Ozacar, Rita Fagan, Rolf Karlstrom.

Friday, June 22   10:45 AM–12:00 NOON
Playhouse Theater

Endodermal and Mesodermal Organs

Chair: Elke Ober

60- 10:45
Cftr functions during zebrafish organogenesis. Adam Navis, Michel Bagnat.

61- 11:00
Phosphatidylinositol Deficiency Leads to ER Stress-Induced Intestinal Epithelial Injury and Inflammation: A Novel Mechanism of Intestinal Inflammatory Diseases. Prakash Thakur, Jon Davison, Carsten Stuckenholz, Adam Amsterdam, Kirsten Sadler, Nathan Bahary.

62- 11:15
Understanding neurod function in the developing endocrine pancreas: a tool to determine beta cell lineage. Gökhan Dalgin, Katie Kindt, Victoria E. Prince.

63- 11:30
Sox9b is a key regulator of pancreaticobiliary ductal system development. M. Delous, C. Yin, D. Shin, N. Ninov, J. Carten, L. Pan, S. Farber, C. Moens, D. Stainier.

64- 11:45
Specification and Allocation of Hepatopancreas Progenitors. Joseph J. Lancman, Danhua Zhang, Keith Gates, Didier Y. R. Stainier, P. Duc Si Dong.

Friday, June 22   10:45 AM–12:00 NOON
Promenade Hall

Cancer and Growth Control

Chair: Joan Heath

65- 10:45
Autophagy induction is a Tp53-independent cell survival response in a new zebrafish model of disrupted ribosome biogenesis. Joan Heath, Yeliz Boglev, Andrew Badrock, Andrew Trotter, Sebastian Markmiller, Elsbeth Richardson, Tanya de Jong-Curtain, Nathan Hall, Annie Ng, Heather Verkade, Elke Ober, Donghun Shin, Chong Hyun Shin, Katherine Hannan, Richard Pearson, Ross Hannan, Seok-Hyung Kim, Kevin Ess, Graham Lieschke, Didier Stainier.

66- 11:00
Zebrafish model to study signaling pathways involved in pancreatic tumour. Marco Schiavone, Elena Rampazzo, Shu Liu, Luca Persano, Giusy Battilana, Alessandro Casari, Andrea Vettori, Natascia Tiso, Enrico Moro, Giuseppe Basso, Steve Leach, Francesco Argenton.

67- 11:15
Development and characterization of new zebrafish melanoma cell lines. Richard M. White, Erin Langdon, Charles Kaufman, Leonard Zon.

68- 11:30
Atypical Wnt Receptor Involvement in Hematopoietic Stem Cell Specification and Leukemia. Wilson K. Clements, David Traver.

69- 11:45
AKT pathway activation drives T-cell acute lymphoblastic leukemia relapse. J. Blackburn, K. Dobrinski, S. Martinez, C. Lee, D. Langenau.

Friday, June 22   1:30 PM–2:30 PM
Overture Hall

Keynote Speaker: Rudolf Jaenisch

Introduction: Alex Schier

Friday, June 22   2:30 PM–3:00 PM
Overture Hall

Chi-Bin Chien Award Presentation
2012 Winner: David Kokel

Chair: Cecilia Moens

70- 2:30
Behavior-based neuroactive drug discovery in the zebrafish. David Kokel.

Saturday, June 23   8:30 AM–9:45 AM
Overture Hall

Emerging Technologies: Genetics and Genomics

Chair: Scott Holley

71- 8:30
Rapid mutant mapping and candidate gene identification using RNA-Seq. Adam Miller, Cecilia Moens.

72- 8:45
Computation and crowdsourcing: a synergistic platform for annotating the zebrafish phenome. Brian Canada, John Schleicher, Ivana Simic, Timothy Cooper, Keith C. Cheng.

73- 9:00
An optimized two-finger archive for efficient ZFN-mediated gene targeting. Ankit Gupta, Ryan Christensen, Amy Rayla, Abirami Lakshmanan, Gary Stormo, Scot Wolfe.

74- 9:15
High success rates and mutation efficiencies of TALENs in zebrafish. Lindsay Cade, Deepak Reyon, Woong Hwang, Shengdar Tsai, Samir Patel, Cyd Khayter, Jeffry Sander, J. Keith Joung, Randall Peterson, J.-R. Joanna Yeh.

75- 9:30
Second generation TALEN scaffold increases frequency of targeted mutations in zebrafish embryos. Jarryd M. Campbell, Ying Wang, Victoria M. Bedell, Kevin I. Neff, Daniel F. Carlson, Colby G. Starker, Daniel F. Voytas, Scott C. Fahrenkrug, Karl J. Clark, Stephen C. Ekker, Jeffrey J. Essner.

Saturday, June 23   8:30 AM–9:45 AM
Capitol Theater

Morphogenesis and Cell Migration

Chair: Tatjana Piotrowski

76- 8:30
Competition between Delta and Epb41l5 for Mib facilitates delamination of neurons. Miho Matsuda, Kinneret Rand, Greg Palardy, Motoyuki Itoh, Ajay Chitnis.

77- 8:45
E-cadherin controls apical cell geometry and orientation of cell division in the zebrafish lens epithelium. T. Mochizuki, S. Suzuki, A. Sakaue-Sawano, A. Miyawaki, I. Masai.

78- 9:00
The PCP proteins Vangl2 and Glypican4 differentially regulate ECM organization during gastrulation. B. Blairanne Williams, Nathan A. Mundell, Julie A. Dunlap, Jason R. Jessen.

79- 9:15
Collective Prechordal Plate Migration Relies on an Intrinsic Directionality Signal Transmitted through Cell Contacts. Julien G. Dumortier, Sandro Martin, Dirk Meyer, Frederic M. Rosa, Nicolas B. David.

80- 9:30
Cell shape changes at the midbrain-hindbrain boundary (MHB) are regulated by non-muscle myosins during vertebrate brain morphogenesis. Jennifer H. Gutzman.

Saturday, June 23   8:30 AM–9:45 AM
Promenade Hall

Hematopoeisis: Development and Disease

Chair: Graham Lieschke

81- 8:30
Genetic fate mapping of draculin-expressing cells redefines the tissue-specific organization of lateral mesoderm. C. . Mosimann, D. Panáková, K. L. Lawson, A. J. Davidson, A. A. Werdich, G. Musso, C. A. MacRae, L. I. Zon.

82- 8:45
Novel Hematopoietic Regulator Drl-L3 Governs Progenitor Cell Differentiation. Wittaya Pimtong, Madhusmita Datta, Allison M. Ulrich, Jennifer Rhodes.

83- 9:00
Tracing developing B cells in a double Tg (CD79b:eGFP, Rag2:mCherry) zebrafish line. Xingjun Liu, Yue-sheng Li, Lingjuan Tang, Susan Shinton, Jennifer Rhodes, Hui Feng, A.Thomas Look, Richard Hardy.

84- 9:15
Foxn1 maintains thymic epithelial cells to support T cell development via MCM2 in zebrafish. Dongyuan Ma, Feng Liu.

85- 9:30
Immunoresponsive gene 1 is essential for mitochondrial ROS production and bactericidal activity within macrophage-lineage cells. C. Hall, R. Boyle, M. Vega Flores, S. Oehlers, K. Crosier, P. Crosier.

Saturday, June 23   10:30 AM–11:45 AM
Overture Hall

Plenary Session IV: Physiology and Disease

Chair: Tanya Whitfield

86- 10:30
Fgf signalling mediates glial bridge formation and supports axonal regeneration after spinal cord injury in zebrafish. Yona Goldshmit, Tamar Sztal, Patricia Jusuf, Thomas Hall, Mai Nguyen Chi, Peter Currie.

87- 10:45
Microglia arise in two waves, with adult populating cells deriving from embryonic erythromyeloid progenitors. V. Wittamer, J. Y. Bertrand, D. Panákova, F. Ellett, G. J. Lieschke, C. MacRae, D. Traver.

88- 11:00
Interorganelle calcium flow underlies ototoxin-induced hair cell death. Robert Esterberg, Dale Haley, Edwin Rubel, David Raible.

89- 11:15
Zebrafish Genetic Screens Identify DLST as a Novel Therapeutic Target for Treating Human Acute T-Lymphoblastic Leukemia/Lymphoma. Hui Feng, Hongling Peng, Daniel Helman, Adam Amsterdam, Takaomi Sanda, John Kanki, A. Thomas Look.

90- 11:30
The Novel Radioprotective Protein Ccdc94 Regulates p53 Expression, DNA Repair and the G2 Checkpoint. Shelly Sorrells, Seth Carbonneau, Erik Harrington, Aye T. Chen, Bridgid Hast, Kaitlin Basham, Brett Milash, Ujwal Pyati, Michael B. Major, Yi Zhou, Rodney A. Stewart, Leonard I. Zon, A. Thomas Look, Cicely Jette.

Sunday, June 24   9:00 AM–10:15 AM
Overture Hall

Early Development and Patterning

Chair: Tom Schilling

91- 9:00
Newly Discovered AP5 complex protein Souffle Controls Endocytosis during Oogenesis. Palsamy Kanagaraj, Amandine Stein, Nadine Vollack, Joan Cerda, Roland Dosch.

92- 9:15
Maternal Y Box Binding Protein 1 Regulates the Timing of Yolk Syncytial Layer (YSL) Formation in Zebrafish. Pooja Kumari, Patrick C. Gilligan, Long Tran Duc, Sylke Winkler, Robin Philp, Karuna Sampath.

93- 9:30
Characterization of the minimum conditions necessary to induce and pattern a complete embryo. Bernard Thisse, Peng-Fei Xu, Karine Ferry, Nathalie Houssin, Christine Thisse.

94- 9:45
DV and AP axial patterning are coordinated by an identical patterning clock. M. Hashiguchi, M. C. Mullins.

95- 10:00
A Dominant Mutation in Variant Histone H3.3 Reveals a Unique Epigenetic Remodeling Event Essential for Neural Crest Multipotency. Samuel Cox, Hyunjung Kim, Woojin An, Gage Crump.

Sunday, June 24   9:00 AM–10:15 AM
Capitol Theater

Sensory Systems

Chair: Miguel Allende

96- 9:00
In Toto Imaging Reveals Cellular Orchestration and FGF Regulation of Epithelial Behaviors that Result in Semicircular Canal Morphogenesis. Ian Swinburne, Sean Megason.

97- 9:15
Kremen1 modulates canonical Wnt signaling in the posterior lateral line primordium. Hillary F. McGraw, Maya D. Culbertson, Alexei V. Nechiporuk.

98- 9:30
ErbB signaling in Schwann cells controls quiescence of lateral line progenitor cells through regulation of Wnt and Fgf signaling. Mark E. Lush, Tatjana Piotrowski.

99- 9:45
The tumor suppressor gene retinoblastoma-1 regulates retinal development and function. Marc A. Wolman, Michael Gyda, Kristin Lorent, Michael Granato.

100- 10:00
Selective axon degeneration as a correction mechanism for pre-target topographic sorting of retinal axons. Fabienne E. Poulain, Chi-Bin Chien.

Sunday, June 24   9:00 AM–10:15 AM
Promenade Hall

Chemical Biology

Chair: Randall Peterson

101- 9:00
Tissue-specific estrogen receptor activation in response to environmental endocrine disruptors. Daniel A. Gorelick, Luke R. Iwanowicz, Alice L. Hung, Junjie Gao, Vicki S. Blazer, John M. Hamlyn, Marnie E. Halpern.

102- 9:15
Structural features for allosteric inhibition of DUSP6 identified by molecular dynamics simulations and in vivo SAR studies. Vasiliy N. Korotchenko, Manush Saydmohammed, Laura L. Vollmer, Ahmet Bakan, Kyle Sheetz, Karl T. Debiec, Kristina A. Greene, Christine S. Agliori, Greg Gibson, Simon C. Watkins, Ivet Bahar, Billy W. Day, Andreas Vogt, Michael Tsang.

103- 9:30
Functional Small Molecule Interrogation of Pancreatic Beta Cell Regeneration Pathways in Adult Zebrafish. Jennifer B. Moss, Larry G. Moss.

104- 9:45
Presynaptic nicotinic acetylcholine receptors in hindbrain regulate acute tolerance to ethanol. Fumihito Ono, Hiromi Ikeda, Alison Delargy, Tohei Yokogawa, Jason Urban, Harold Burgess.

105- 10:00
Small Molecules Rescuing Doxorubicin Induced Cardiomyopathy. Yan Liu, Lin Zou, Kumar Sakar, Jordan Shin, Wei Chao, Randall Peterson.

Sunday, June 24   9:00 AM–10:15 AM
Wisconsin Studio

Muscle, Skin and Connective Tissue

Chair: Shannon Fisher

106- 9:00
Characterization of zebrafish models of Filamin related myofibrillar myopathy. Avnika A. Ruparelia, Mo Zhao, Peter D. Currie, Robert J. Bryson-Richardson.

107- 9:15
Opposing activities of Pbx and Prdm1 transcription factors regulate skeletal muscle fiber type differentiation. Lisa Maves, Cecilia Moens, Stephen Tapscott.

108- 9:30
Skin to Swim In: Uncovering novel epidermal biology with the Zebrafish Integument Project and novel mutants wicked witch of the Midwest and scheherazade. Stephanie E. Westcot, Karl J. Clark, Gary L. Moulder, Kimberly J. Skuster, Mark D. Urban, Victoria M. Bedell, Melissa S. McNulty, Tammy M. Greenwood, Rebecca J. Richardson, Matthias Hammerschmidt, Stephen C. Ekker.

109- 9:45
Modulation of Smooth Muscle Contraction in the Zebrafish Intestine by the High Molecular Weight Caldesmon Isoform. Joshua Abrams, Gangarao Davuluri, Christoph Seiler, Michael Pack.

110- 10:00
Cleft-palate-associated gene Interferon Regulatory Factor 6 promotes differentiation of the periderm by activating expression of Grainyhead like 3. Robert A. Cornell, Gabriel de la Garza, J. Robert Schleiffarth, Dan Wagner.

Sunday, June 24   10:45 AM–12:00 NOON
Overture Hall

Plenary Session V: Morphogenesis and Organogenesis

Chair: Kate Whitlock

111- 10:45
Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. Stephanie Woo, Michael Houseley, Orion Weiner, Didier Stainier.

112- 11:00
Cell Rearrangement after Noisy Morphogen-based Specification Underlies Precise Progenitor Domain Pattern Formation in the Ventral Neural Tube. Fengzhu Xiong, Peng Huang, Andrea Tentner, Paul Cowgill, Arnaud Gelas, Kishore Mosaliganti, Lydie Souhait, Nicolas Rannou, Ian Swinburne, Nikolaus Obholzer, Alexander Schier, Sean Megason.

113- 11:15
Clonally dominant cardiomyocytes direct heart morphogenesis. Vikas Gupta, Ken Poss.

114- 11:30
In vivo analysis of axonal transport defines JNK-interacting protein 3 (Jip3) as a direct mediator of retrograde axonal transport of discrete cargo. Catherine Drerup, Gary Banker, Alex Nechiporuk.

115- 11:45
Germ cell loss induces female-to-male sex reversal in the adult zebrafish. Daniel B. Dranow, Bruce W. Draper.

2012 Important Dates: