Welcome to the IKMC

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The International Knockout Mouse Consortium (IKMC) aims to mutate all protein-coding genes in the mouse using gene trapping and gene targeting in C57BL/6 ES cells. Read more...

Download the IKMC Gene List
View targeting strategies
View all allele types

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help Search IKMC database
Enter gene symbols, gene IDs or genome location

e.g., Adam19, Pax, ENSMUSG00000020681, Chr13:22210730-22311689
(coordinates from NCBI mouse genome assembly 37)
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Use the following links to browse genes
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Status

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Number of genes for which IKMC ES cells with a given allele type are available. Overlaps indicate the number of genes for which 2 or 3 types of alleles have been generated.

Targeted alleles

Total Genes KOMP EUCOMM/
EUCOMMTools
NorCOMM mirKO
CSD Regeneron
Vectors available 6593 4733 8255 839
ES cells available 5250 3959 6887 569 230
Mutant mice available 402 349 647 4
View details and project goalsView details about the acronyms used

Gene trap alleles

Total Genes TIGM EUCOMM NorCOMM
ES cells available 9397 4416 4593
Mutant mice available 86 10
NOTE: Not all gene traps are in C57BL/6 ES cells. View strain information




See how researchers are using IKMC products

News

July 2011 Mouse Molecular Genetics (A Wellcome Trust Scientific Conference), 20-23 September 2011, Hinxton, Cambridge, UK
June 2011 Nature News: Mouse library set to be knockout
June 2011 Wellcome Trust Advanced Course: Genetic Manipulation of ES Cells, 31 October - 13 November 2011
May 2011 Martsearch interface released
March 2010 KOMP and EUCOMM alleles

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