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Welcome to the Eddy/Rivas lab at the Janelia Farm Research Campus of the Howard Hughes Medical Institute. Our research interests are in computational genome sequence analysis. We use probabilistic modeling techniques to develop new algorithms to find features in DNA, RNA, and protein sequences. One of our primary interests is in identifying novel structural and catalytic RNAs. Another is to recognize remote protein sequence homologies. We focus in particular on development of practical software tools that implement probabilistic inference algorithms for large scale sequence analysis.
Since moving to Janelia Farm in 2006, we have begun to take interest in new problems at the interfaces between neuroscience, genomics, computation, and Bayesian statistical inference.
[More about our current research interests...]
Discovery of Pyrobaculum Small RNA Families With Atypical Pseudouridine Guide RNA Features.
D. L. Bernick, P. P. Dennis, M. H\"ochsmann, T. M. Lowe.
RNA, in press, 2012.
An Improved Greengenes Taxonomy with Explicit Ranks for Ecological and Evolutionary Analyses of Bacteria and Archaea.
D. McDonald, M. N. Price, J. Goodrich, E. P. Nawrocki, T. Z. DeSantis, A. Probst, G. L. Andersen, R. Knight, P. Hugenholtz.
ISME J., in press, 2011.
[abstract] [reprint]
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[More about databases and servers we make available...]
HHMI Janelia Farm Research Campus
19700 Helix Drive
Ashburn, VA 20147, USA
Phone: 571.209.4000 [this is the general Janelia operator number, not an office]
[More about people in the lab and their contact info...]